Minutes of the AEJEG 4th June 2024

Meeting of the Committee at 09:30 on Tuesday 4th June 2024 via Microsoft Teams

Contents

Announcements

1. Members welcomed Prof Shirley Price to the AEJEG. 

Interests   

2. No conflicts of interest were declared.   

Item 1: Welcomes and Apologies for absence   

3. No apologies were received. 

Item 2: RP1457 Update on Application for Authorisation of the substance RP1457 Update on Application for Authorisation of the substance glycolipids (E 246) (Nagardo, AM-1) for use as a new food additive (RP1457) (Reserved) Update Paper AEJEG/2024/01  

4. The AEJEG has been presented with an updated cover paper including all previous RFI responses to allow for a review of Regulated Products Application RP1457 in its totality. 

5. This Application is for the authorisation of the substance Glycolipids (E 246) also known as Nagardo and AM-1, for use as a new food additive. The substance has antimicrobial effects and therefore is proposed for use in beverages with a normal use level of 10 mg/l and a maximum proposed level of up to 50 mg/l.  

6. Glycolipids (E 246) had previously been presented at the 13th February 2023 meeting in which a RFI was raised, the responses to this RFI were presented to the AEJEG at the meeting on 20th July 2023, and a further RFI was raised on the 10th August 2023. The AEJEG met to discuss the Toxicological studies submitted for RP1457 on its meeting on 8th September 2023, due to the nature of some of the studies received, a Member of the Committee on Toxicity of Chemicals in Food, Consumer Products, and the Environment (COT) attended the meeting to assist the AEJEG in these discussions. During the September meeting, the AEJEG agreed that no conclusions could be drawn on this data until further data on the antimicrobial properties of Glycolipids (E 246) had been received from the Applicant. A further RFI had been sent to the Applicant on Wednesday 8th November 2023 and a response was received on the 29th February 2024.  

7. The final RFI response had been discussed in the April 2024 meeting where it had been agreed that RP1457 would return to the AEJEG as an updated cover paper with inclusion of all the received RFI information to allow the AEJEG to review the entire dossier in its totality. 

8. Overall, the AEJEG commented that there was no toxicity or genotoxicity concerns and agreed on a NOAEL  

9. The Secretariat stated they would prepare a Committee Advice Document capturing the discussions and conclusion which the AEJEG can review in a later meeting Once signed off by the AEJEG this Document will be presented to The Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) 

Item 3: Minutes from the last meeting - AEJEG/2024/04  

10. Members were represented with the minutes of the AEJEG meeting held on the 16th April 2024. 

11. The minutes of the last meeting were agreed as accurate record, subject to minor editorial changes. 

Item 4: Any other business 

12. Members were reminded that if they were contacted by any members of the public to forward the communication to the AEJEG Secretariat and FSA Officials will address the communication. 

13. Members were informed that the next AEJEG meeting will be held on the 18th of July and the next Smoke Flavourings will be the 25th of July 2024.